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Clinicians powering AI alignment, training & safety.

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© 2026 EnterTheLoop Ltd · Built in Britain

Methodology

Rigour you can take to a regulator.

Every clinical AI evaluation we run is calibrated against expert consensus, scored with proper rules, and reported with confidence intervals — reproducible from raw judgement to the final Reliability Report. The same standard builds the datasets we curate.

Talk to our teamThe 12 failure modes
Evaluation pipelineReproducible
01

Calibrate

Two-phase · gold-anchored

02

Score

Brier · Log · CIs

03

Agree

Cohen's & Fleiss' κ

Reliability Report

PDF + JSON · per-metric CIs

Issued
Clinician-led · methodology versioned · audit trail attached
Calibration

Two-phase calibration.

Every evaluator is calibrated against expert consensus before they assess your AI — first a fast screen, then a full statistical calibration. The same pathway runs for every profession, so a score means the same thing whoever earned it.

Gold-Standard Screen
11 tasks
G-01Drug interaction check
G-02Dosage boundary test
G-03Contraindication ID
G-04Guideline alignment
G-05Scope boundary
G-06Risk severity rating
G-07Triage priority
G-08Lab interpretation
G-09Side effect flagging
G-10Clinical summary
Expert Alignment9/10 — Pass

Phase 1 — Quick Screen

An 11-task sequential screen on gold-standard items with known expert consensus. Anti-luck guardrails and per-item agreement thresholds confirm an evaluator's judgement is aligned with the reference standard before they commit to the full calibration. ~20 minutes.

Sequential Analysis
Converged
After 5 tasks72%
±18%
After 10 tasks81%
±12%
After 15 tasks86%
±8%
After 20 tasks89%
±5%
After 23 tasks91%
±3.2%

Result

Stopped at task 23 — CI narrowed below 5%

Score

91% ± 3.2%

Phase 2 — Full Calibration

A complete statistical calibration across all eight RLHF task types — rating, comparison, ranking, rubric, correction, annotation, justification, and red-team. Produces the reliability score with Beta-Binomial / bootstrap intervals per metric, and forms the basis of the Reliability Report. 60–90 minutes.

Scoring

Proper scoring rules.

We score with mathematically proper rules that reward honest, well-calibrated judgement — and report the uncertainty around every number rather than a bare point estimate.

Brier Score
0 = perfect
E-0190% → 85%
0.12
E-0270% → 72%
0.08
E-0395% → 60%
0.42
E-0480% → 78%
0.09
E-03 flaggedOverconfident

Brier Score

Measures the accuracy of probabilistic predictions. A proper scoring rule that rewards well-calibrated confidence — penalising overconfidence and underconfidence equally.

Log Score
Sharp penalty
Well-calibrated
80%-0.22
Slightly over
92%-0.51
Overconfident
99%-2.30

99% confidence on wrong answer → 10× penalty vs Brier

Log Score

Sharper discrimination between good and poor calibration than the Brier score — particularly good at catching evaluators who are systematically overconfident in their clinical assessments.

95% CI
LCB ≥ 85%
C-0191%(87–95%)
Pass
C-0286%(80–92%)
Fail
C-0393%(90–96%)
Pass

C-02: 86% point estimate but LCB 80% — below threshold

Confidence Intervals

Beta-Binomial intervals for proportions, bootstrap intervals for continuous metrics, and lower confidence bounds for certification — so every score reflects worst-case plausible performance, not just a point estimate.

Agreement

Inter-annotator agreement.

We measure how much evaluators agree — correcting for chance — so we can tell genuine clinical disagreement apart from noise, and report the reliability of the process itself.

Pairwise Agreement
2 evaluators
ItemEval AEval BMatch
#1SafeSafe
#2UnsafeUnsafe
#3SafeBorderline
#4UnsafeUnsafe
#5BorderlineBorderline
#6SafeSafe
#7UnsafeSafe
#8SafeSafe

Observed agreement

75% (6/8 items)

Cohen's κ

0.71 — Substantial

0 (chance)1 (perfect)

Cohen's Kappa (κ)

Pairwise agreement between two evaluators, corrected for chance. Used for direct comparison tasks and pairwise annotation where each item is assessed by exactly two people.

Multi-Rater Agreement
4 evaluators
Item
R1R2R3R4
Agree
#1
AAAB
83%
#2
BBBB
100%
#3
ABAA
83%
#4
CCBC
83%
#5
ABCA
50%
#6
BBBA
83%

Categories

ABC

Fleiss' κ

0.62 — Substantial

0 (chance)1 (perfect)

Fleiss' Kappa (κ)

Extends agreement to multiple evaluators — essential for production work where items are assessed by varying numbers of clinicians and we need the overall reliability of the process.

Quality control

Five layers in production.

Calibration gets an evaluator in the door. These five controls keep the quality there — running continuously through live work, not just at the start.

01

Gold-standard injection

Known-answer tasks are randomly seeded into production queues. Evaluators can't tell which items are gold, so quality holds on every response — not just when they think they're being watched.

02

Drift detection

Statistical monitoring flags when an evaluator's performance starts to drift from their calibration baseline — catching fatigue, disengagement, or shifting standards early.

03

Attention checks

Strategically placed verification items confirm evaluators are reading and reasoning, not pattern-matching or rushing.

04

Skip budget

Evaluators can skip tasks outside their expertise, within a managed budget — preventing gaming while allowing honest acknowledgement of limits.

05

Justification quality

Multi-signal analysis of written rationale assesses depth, clinical reasoning, and consistency — surfacing thin or formulaic explanations that signal disengagement.

Readiness

Readiness scoring.

Before any paid work, we compute a readiness score across three task families — so the right evaluator is matched to the right project, with the evidence to back it.

Readiness Profile87%
RankingCorrectionAssessmentCalibrationConsistency

Ranking & Correction

Pairwise ranking, text correction, and response assessment — the core RLHF task families.

Threat Coverage86%
HallucinationDosage ErrorScope CreepBias DetectionOmission86%ready

Safety & Red-Teaming

Adversarial testing across failure-mode categories — identifying dangerous outputs before they reach patients.

Annotation Skills88%
LabellingClassificationExtractionAnnotation88%ready0%100%

Data & Annotation

Clinical data labelling, document classification, and structured annotation for AI training datasets.

Datasets

High-quality datasets, built sovereign.

The same rigour that grades a model can build the data that trains it. We apply our sovereign methodology to commercial datasets too — the same standard, kept firewalled from the sovereign programme so your data and IP stay yours.

Clinically authentic

Grounded in how senior UK clinicians actually reason about real patients — so the data carries the judgement that makes medical AI safe where it matters.

Built to last

Clinical practice never stands still, and neither do our datasets. They're built to stay anchored to current UK practice, so quality holds up long after delivery.

Authored, not scraped

The expertise that matters can't be scraped from the open web — it comes from verified UK clinicians, captured at the depth and rigour serious medical AI demands.

Sovereign methodology

Same methodology. Firewalled from the sovereign side.

Your commercial datasets are built to the same standard — but kept strictly firewalled from our sovereign programme. Your data and IP stay yours: curated and held onshore under a documented, auditable process, never folded into the shared sovereign asset. The methodology behind it is our core IP, shared only under NDA.

Explore Sovereign AIDataset services
United Kingdom — data and IP held onshore
The Deliverable

Every engagement ends in a Reliability Report.

A procurement-grade artifact — reproducible on demand, with the full methodology referenced throughout. Built for the people who ask the hardest questions: procurement, regulators, and your safety review board.

Talk to our teamThe 12 failure modes
Inside the reportProcurement-grade
  • 01

    PDF + JSON

    Human-readable for safety reviews; machine-readable for ingestion into your QMS or evidence pipeline.

  • 02

    Per-metric confidence intervals

    Beta-Binomial intervals for proportions, bootstrap for continuous scores — a lower confidence bound on every metric.

  • 03

    Readiness scores

    Overall, safety-critical, and annotation-heavy readiness, each backed by the underlying calibration data.

  • 04

    Full audit trail

    Evaluator IDs, gold-task agreement, attention-check history, and methodology version recorded against every result.

Scope a project

30-minute call. Get a quote.

Tell us what you’re building and what you need evaluated, red-teamed, annotated, or generated. We’ll come back with a fixed-price brief — no long enterprise procurement.

  • Fixed-price quote
  • No drawn-out procurement process

NDA available on request.

EnterTheLoopentertheloopClinicians powering AI alignment, training & safety.

Verified against

GMCNMCGPhCHCPC

Follow

Register→
© 2026 EnterTheLoop Ltd  ·  Built in Britain
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EnterTheLoopentertheloop

Clinicians powering AI alignment, training & safety.

PrivacyTermsCookies
© 2026 EnterTheLoop Ltd · Built in Britain